This region tends to appear at the N-terminus of proteins alsocontaining DNA-binding HMG (high mobility group) boxes(Pfam:PF00505) and appears to bind the armadillo repeat ofCTNNB1 (beta-catenin), forming a stable complex. Signaling byWnt through TCF/LCF is involved in developmental patterning,induction of neural tissues, cell fate decisions and stem celldifferentiation [3]. N-terminal CTNNB1 binding CTNNB1_binding